Products
We are able to synthesise a wide range of modified oligonucleotides and oligonucleotide analogues, some examples of which are given below.
Please enquire if you have any other requirements.
Fluorescent and fluorogenic oligonucleotides
We can incorporate a wide range of fluorophores and fluorescence quenchers into oligonucleotides at the 5′-end, at the 3′-end or internally for use in genetic and genome analysis.
Examples are FAM, HEX, TET, Cy3, Cy5, JOE, ROX, and TAMRA.
Modified bases
Oligonucleotides containing inosine, universal bases, 2-aminopurine and many other modified bases.
Amino-modified, thiol-modified and biotinylated oligonucleotides
Labels can be incorporated at either end or internally.
Forensic science
Small and large scale synthesis of fluorescent and unlabelled STR primers.
Large-scale synthesis for biophysical studies
Highly pure oligonuleotides in multi-milligram quantities for biophysical studies such as nmr or X-ray crystallography.
Biomedical applications
Backbone modified oligonucleotides for in vivo and cell culture studies
Nanotechnology
Labelled and chemically modified oligonucleotide scaffolds for nanotechnology applications.
Oligonucleotide analogues
Unlabelled and fluorescently labelled PNA oligomers.