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Working in the field of nucleic acids research, Tom and Dorcas received many enquiries from researchers around the world frustrated with the general lack of quality in oligos they were receiving. Tom and Dorcas started making occasional oligos for free, as a favour to friends, who found that these oligos worked in experiments where other oligos had failed. The number of requests increased, and ATDBio was born.
At ATDBio we still put quality first, and believe that our attention to detail combined with years of experience and a knowledge of the latest developments in nucleic acids chemistry enables us to provide an unrivalled service. We work with both small academic groups and large biotech companies, and early-stage partnerships with ATDBio have been critical in the growth of several such companies.
Collectively, the directors of ATDBio, have well over 50 years' experience in nucleic acids chemistry.
Prof. Tom Brown is one of the world's leading nucleic acids chemists. He began working on nucleic acids in the late 1970s, during his PhD at Bradford University, before moving to Oxford University and then Cambridge University, where he worked with Dr Olga Kennard, OBE, FRS, a pioneer of DNA crystallography. In 1985 Tom was appointed to a lectureship in Biological Chemistry at Edinburgh University, where he was subsequently promoted to Reader and then Professor of Nucleic Acids Chemistry, and, in 1995, he moved to Southampton University as Professor of Chemical Biology. In October 2013, Tom was appointed Professor of Nucleic Acid Chemistry at the University of Oxford (shared between the chemistry and oncology departments).
Throughout his career, Prof. Brown has pioneered many new technologies in the chemistry and biology of nucleic acids, including the development of Scorpion primers in collaboration with DxS Ltd. More recently, several high profile publications have resulted from Prof. Brown's research on the use of click chemistry in DNA and RNA ligation, including the use of click chemistry in oligo synthesis. This constant stream of innovations has a direct impact on the service ATDBio provides to its customers. When customers ask us for tricky oligos, we can often suggest new ways of making them based on research that has not even been published, all without compromising on quality.
Prof. Brown has published over 300 papers and patents in the nucleic acids field, and his research group is more active now than ever. He has won several prizes including the Royal Society of Chemistry Nucleic Acids Chemistry Prize (2007) and the Royal Society of Chemistry Interdisciplinary Award (2009). Tom is a serial entrepeneur, having founded three successful companies: ATDBio, PrimerDesign and Oswel Research Products.
Dorcas Brown completed a PhD at Bradford University before moving to Oxford and Cambridge, where she developed methods for oligonucleotide synthesis, and then Edinburgh. She established Oswel Research Products Ltd with Tom at Edinburgh University in 1985 and worked as Lab Manager at Oswel, overseeing a move to Southampton, until the company was sold in 2001. In 2005, Dorcas and Tom started ATDBio, where Dorcas manages the Southampton lab.
Tom (Jr) completed his degree and D.Phil. in chemistry and chemical biology at the University of Oxford, before joining ATDBio full-time in 2010. Tom set up ATDBio's new R&D laboratory in Oxford in 2013, and manages the Oxford lab.
Asha has a degree and D.Phil. in chemistry from the University of Oxford, where she now works as a post-doctoral researcher.
We wrote the book. Read our Nucleic Acids Book, an exclusive online guide to the chemistry and biology of nucleic acids.
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